Lichen amyloidosus: a bullous variant.

نویسندگان

  • B P Khoo
  • Y K Tay
چکیده

INTRODUCTION Lichen amyloidosus is a common skin disease seen among Asian patients. CLINICAL PICTURE Typical features range from macular hyperpigmentation to pruritic, lichenified, hyperpigmented papules. However, in this rare bullous variant of lichen amyloidosus, bullae and vesicles are present. Histopathologically, deposits of amyloid were seen in the papillary dermis, associated with an intraepidermal or subepidermal blister. TREATMENT AND OUTCOME No good treatment so far, but pruritus can be relieved by topical steroid. CONCLUSION It is important to screen for systemic amyloidosis with the relevant investigations as it can present similarly with blistering eruptions, in which the prognosis would be grave.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Lichen amyloidosus without itching indicates that it is not secondary to chronic scratching.

Sir, The origin of lichen amyloidosus (LA) is controversial. It is a form of primary cutaneous amyloidosus in which fibrillar proteinaceous material is deposited solely in the skin, without associated systemic manifestations. LA is typically highly pruritic, and the deposition of fibrillar material has generally been considered to be secondary to the scratching induced by other subjacent prurit...

متن کامل

Lichen planus pemphigoides: A case report

Lichen planus pemphigoides (LPP) is a rare autoimmune blistering disease that is characterized by the development of vesico-bullous skin lesions in patients with lichen planus. The histopathology of LPP reveals a sub_epidermal blister with linear deposition of IgG and /or C3 along the dermal_epidermal junction (DEJ) upon direct immunofluorescence (DIF). We hereunder describe a case of lichen pl...

متن کامل

Extragenital bullous lichen sclerosus.

Lichen sclerosus is an inflammatory skin condition characterized by inflammation of the papillary dermis that leads to white scarlike plaques. It occurs classically in the genitals but also has extragenital manifestations with a variety of clinical presentations including a bullous variant. The purpose of this review is to characterize extragenital bullous lichen sclerosus, suggest that it may ...

متن کامل

Remission of lichen amyloidosus after treatment with acitretin.

Lichen amyloidosus Retinoids Apoptosis Norbert Reider, MD, Department of Dermatology, University of Innsbruck, Anichstrasse 35, A-6020 Innsbruck (Austria) In September 1993, a 72-year-old woman presented at our Department with an eruption of reddish brown, coalescent, hyperkeratotic, extremely pruritic papules of her thighs (fig. 1), the extensor surfaces of both forearms and the lumbosacral ar...

متن کامل

Bullous and hemorrhagic lichen sclerosus - Case report*

Lichen sclerosus is a chronic inflammatory disease, usually located in the genital area. The etiology of lichen sclerosus is multifactorial, with participation of genetic, autoimmune, infectious and hormonal factors. Bullous clinical form stems from hydropic degeneration of the basal membrane, constituting a less frequent variant of the disease. In this work, we report the case of a female pati...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Annals of the Academy of Medicine, Singapore

دوره 29 1  شماره 

صفحات  -

تاریخ انتشار 2000